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COVID-19

Risk factors for COVID-19 complications

Goal
To identify factors associated with COVID-19 complications from the complete medical records of a nationally representative SARS-CoV-2 infected cohort
Impact
Reliably identifying patients at increased risk for COVID-19 complications could guide clinical decisions, public health policies, and preparedness efforts
Collaborator(s)
Maccabi Institute for Research and Innovation

The COVID-19 pandemic poses grave challenges to patients, healthcare providers, and policy-makers. Many of these challenges may be better addressed with timely stratification of patients into risk groups, based on their past and current medical characteristics. Most studies that characterized at-risk patients explored condition-specific patient cohorts or had limited access to patients’ medical history; thus, investigating related questions and, potentially, obtaining biased results.

 

Our research efforts focus on data from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individuals from a large nationwide health organization to identify those who suffer from serious complications. We compare the prevalence of pre-existing conditions, extracted from electronic health records (EHRs), between COVID-19 patient cohorts with and without complications to identify the conditions that significantly increase the risk of disease complications in various age and sex strata.

Reference(s)

Yanover C, Mizrahi B, Kalkstein N, Marcus K, Akiva P, Barer Y, Shalev V, Chodick G
What Factors Increase the Risk of Complications in SARS-CoV-2–Infected Patients? A Cohort Study in a Nationwide Israeli Health Organization
JMIR Public Health Surveill 2020;6(3):e20872

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